{"title":"L-Lysine","description":"\u003ch2 data-start=\"532\" data-end=\"584\" style=\"text-align: center;\"\u003e\u003cstrong data-start=\"532\" data-end=\"584\"\u003eL-Lysine for Immune Support, Recovery \u0026amp; Wellness\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp data-start=\"686\" data-end=\"1003\" style=\"text-align: center;\"\u003eL-Lysine is an essential amino acid that plays an important role in \u003cstrong data-start=\"754\" data-end=\"779\"\u003eimmune system support\u003c\/strong\u003e, \u003cstrong data-start=\"781\" data-end=\"802\"\u003eprotein synthesis\u003c\/strong\u003e, and \u003cstrong data-start=\"808\" data-end=\"825\"\u003etissue repair\u003c\/strong\u003e. Because the body cannot produce lysine on its own, supplementation can help support daily nutritional needs, especially during periods of physical stress or increased activity.\u003c\/p\u003e\n\u003cp data-start=\"1005\" data-end=\"1316\" style=\"text-align: center;\"\u003eThis collection features high quality \u003cstrong data-start=\"1043\" data-end=\"1067\"\u003eL-Lysine supplements\u003c\/strong\u003e, including capsules, tablets, powders, and combination formulas designed for daily wellness and recovery support. L-Lysine is commonly used to support immune health, collagen formation, and overall recovery as part of a balanced supplement routine.\u003c\/p\u003e\n\u003cp data-start=\"1318\" data-end=\"1579\" style=\"text-align: center;\"\u003eLysine supplements are non-stimulant and versatile, making them suitable for athletes, active individuals, and those focused on immune and wellness support. These formulas can be taken on their own or stacked with other amino acids and immune support nutrients.\u003c\/p\u003e\n\u003cp data-start=\"1581\" data-end=\"1684\" style=\"text-align: center;\"\u003e\u003cstrong data-start=\"1581\" data-end=\"1610\"\u003eShop L-Lysine supplements\u003c\/strong\u003e formulated for purity, potency, and everyday immune and recovery support.\u003c\/p\u003e","products":[{"product_id":"controlled-labs-purple-wraath","title":"Purple Wraath","description":"\u003cp style=\"text-align: center;\"\u003e\u003cspan style=\"font-size: 10pt; color: #000000;\"\u003eTHIS PRODUCT HAS BEEN DISCONTINUED.  \u003ca href=\"https:\/\/www.tigerfitness.com\/pages\/search-results-page?q=eaa\"\u003eClick Here\u003c\/a\u003e for more options!\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 10pt; color: #000000;\"\u003e \u003c\/span\u003e\u003cspan style=\"color: #000000;\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv align=\"center\"\u003e\u003cspan style=\"font-size: 14pt; color: #000000;\"\u003e\u003cstrong\u003eControlled Labs Purple Wraath | Now on sale at TigerFitness\u003c\/strong\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003eDiscover the \"Holy Grail\" of bodybuilding and athletic performance enhancement:\u003c\/span\u003e maximizing lean gains and fat loss while enhancing recovery and increasing strength, endurance, and energy. Purple Wraath was created to be the most complete EAA\/BCAA product on the market; keeping your body in a constant anabolic state and keeping you training hard with its added super endurance complex.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold; font-size: 12pt; color: #000000;\"\u003eKey Attributes:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eFast absorption\/fast acting\u003c\/li\u003e\n\u003cli\u003eEAA \u0026amp; BCAA\u003c\/li\u003e\n\u003cli\u003eCaffeine-free ergogenic formula\u003c\/li\u003e\n\u003cli\u003eDelicious tangy grape flavor\u003c\/li\u003e\n\u003cli\u003eNatural anabolic environment\u003c\/li\u003e\n\u003cli\u003eIncrease athletic performance, endurance, focus, stamina, and muscle recovery\u003c\/li\u003e\n\u003cli\u003eLegal, safe, and effective for both men and women\u003c\/li\u003e\n\u003cli\u003eStimulate metabolism to reduce body fat\u003c\/li\u003e\n\u003cli\u003eExplosive strength, power, and energy\u003c\/li\u003e\n\u003cli\u003eIncrease or maintain muscle mass whether cutting or bulking\u003c\/li\u003e\n\u003cli\u003eDextrose\/maltodextrin free\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eSound too good to be true? Keep reading...\u003c\/p\u003e\n\u003cp\u003eWe all know that supplements are not a replacement for nutrition and training, but if you are looking for a supplement to enhance every part of your workout and take your gains to the next level... look no further than Purple Wraath by Controlled Labs.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold; font-size: 12pt; color: #000000;\"\u003ePurplEAA Complex:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eThe Purple Wraath PurplEAA Complex is a very efficient formula based on the science of actual homo sapiens muscle protein and clinical studies on human amino acid assimilation. Essential Amino Acids (EAA's) are the \"building blocks\" of lean muscle mass, but the EAA's from whey protein can take hours to enter circulation. The solution is the Purple Wraath fast-acting, free-form PurplEAA Complex:\u003c\/p\u003e\n\u003cp\u003eWhile essential amino acids function cohesively as a group to aid in your training, additionally they each produce a significant benefit when it comes to training:\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003eLeucine:\u003c\/span\u003e\u003cbr\u003e- Primary anabolic trigger\u003cbr\u003e- Enhance recovery\u003cbr\u003e- Optimize hormone levels\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003eValine:\u003c\/span\u003e\u003cbr\u003e- Energy \u003cbr\u003e- Recovery \u003cbr\u003e- Glucose production \u003cbr\u003e- Nitrogen balance\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003eIsoleucine:\u003c\/span\u003e \u003cbr\u003e- Energy \u003cbr\u003e- Recovery \u003cbr\u003e- Glucose production \u003cbr\u003e- Hormones\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003eLysine:\u003c\/span\u003e\u003cbr\u003e- Beta-oxidation \u003cbr\u003e- Nitrogen balance \u003cbr\u003e- Calcium absorption \u003cbr\u003e- Energy\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003eArginine:\u003c\/span\u003e \u003cbr\u003e- Vasodilator \u003cbr\u003e- Nutrient delivery \u003cbr\u003e- Anti-Catabolic\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003eHistidine:\u003c\/span\u003e\u003cbr\u003e- Vasodilator \u003cbr\u003e- Sexual function\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003eThreonine:\u003c\/span\u003e \u003cbr\u003e- Nutrient uptake \u003cbr\u003e- Immune system\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003eMethionine:\u003c\/span\u003e \u003cbr\u003e- Enhance metabolism \u003cbr\u003e- Energy \u003cbr\u003e- Mood \u003cbr\u003e- Antioxidant\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003ePhenylalanine:\u003c\/span\u003e \u003cbr\u003e- Energy \u003cbr\u003e- Hormones \u003cbr\u003e- Mood\u003c\/p\u003e\n\u003cp\u003eIt's important to understand that our EAA Complex includes all of the BCAA's (Branched Chain Amino Acids) that you have used in the past, including a precise ratio of leucine. Research shows that blood levels of these KEY amino acids are directly related to muscle protein synthesis, so we formulated a comprehensive and efficient matrix to enhance lean mass directly and indirectly, and under various conditions. Now, that ratio is important, but there are some other very exciting points about this formula. Unlike some of the amino acid supplements on the market, you aren't paying for cheap \"filler\" ingredients such as dextrose or maltodextrin when you purchase Purple Wraath. Also, we chose not to include the amino acid glutamine since it is not an essential amino acid, and our bodies can synthesize it on its own in sufficient quantities. Because the studies that we based this formula off of do not use tryptophan and since it has the potential for \"sedative\" like side affects, we designed Purple Wraath to be completely tryptophan-free.\u003c\/p\u003e\n\u003cp\u003eBy combining intense exercise or weightlifting with the fast absorbing PurplEAA Complex you can rush nutrients into the active cells of your working muscles, creating an anabolic environment optimal for recovery and lean mass.\u003c\/p\u003e\n\u003cp\u003eWhat would an EAA product be without some amazing support ingredients? Good, but not great. To make this formula great we added the PurplEndurance Complex.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold; font-size: 12pt; color: #000000;\"\u003ePurplEndurance Complex:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eYou can't create an optimal anabolic environment without intensity so Controlled Labs decided to take things to the extreme with Purple Wraath by including the ultimate caffeine-free Ergogenic Complex:\u003c\/p\u003e\n\u003cp\u003eSo what does each of the ingredients in the PurplEndurance Complex do?\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003eBeta-Alanine:\u003c\/span\u003e \u003cbr\u003e- Helps increase aerobic efficiency \u003cbr\u003e- Helps enhance oxygen transport \u003cbr\u003e- Helps to reduce lactic acid accumulation\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003eCitrulline Malate:\u003c\/span\u003e \u003cbr\u003e- Reduces Lactic Acid and Ammonia \u003cbr\u003e- Boosts energy production \u003cbr\u003e- Has an oxygen sparing effect \u003cbr\u003e- Boosts mitochondrial function\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003eBetaine Anhydrous:\u003c\/span\u003e \u003cbr\u003e- Is a key osmotic\/cellular hydration ingredient \u003cbr\u003e- Enhances muscle fullness \u003cbr\u003e- Acts as an energy enzyme protector \u003cbr\u003e- Induces the conversion of homocysteine to methionine \u003cbr\u003e- Elevates glutathione levels \u003cbr\u003e- Promotes liver health \u003cbr\u003e- Helps you maintain intracellular electrolytes \u003cbr\u003e- Enhances metabolism\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003eGinger:\u003c\/span\u003e \u003cbr\u003e- Aids in nutrient absorption \u003cbr\u003e- Enhances digestion\/stomach function \u003cbr\u003e- Produces a nootropic effect\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003eNorvaline:\u003c\/span\u003e \u003cbr\u003e- Helps elevate naturally occurring eNOS\u003c\/p\u003e\n\u003cp\u003eAs you can see, we have responded to customer demand and the result: Purple Wraath...the most advanced pre-workout product available!!\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003eREFERENCES\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eBorsheim, E., Tipton, K., Wolf, S. \u0026amp; Wolfe, R. (2002)\u003cbr\u003eEssential amino acids and muscle protein recovery from resistance exercise\u003cbr\u003eAmerican Journal of Physiology, 283(4), E648-E657\u003c\/p\u003e\n\u003cp\u003eBrooks, G. (1987).\u003cbr\u003eAmino acid and protein metabolism during exercise and recovery \u003cbr\u003eMedicine and Science in sports and Exercise, 19(5), S150-S156\u003c\/p\u003e\n\u003cp\u003eRasmussen, B., Tipton, K., Miller, S., Wolf, S. \u0026amp; Wolfe, R. (2000)\u003cbr\u003eAn oral essential amino acid-carbohydrate supplement enhances protein anabolism after resistance exercise\u003cbr\u003eJournal of Applied Physiology, 88, 386-392\u003c\/p\u003e\n\u003cp\u003eTipton, K., Rasmussen, B., Miller, S., Wolf, S., Owens-Stovall, S., Petrini, B. \u0026amp; Wolfe, R. (2001)\u003cbr\u003eTiming of amino acid-carbohydrate ingestion alters anabolic response of muscle to resistance exercise\u003cbr\u003eAmerican Journal of Physiology, Endocrinology, and Metabolism, 281, E197-E206\u003c\/p\u003e\n\u003cp\u003eBohe J, Low A, Wolfe RR, Rennie MJ. (2003)\u003cbr\u003eHuman muscle protein synthesis is modulated by extra cellular, not intramuscular amino acid availability: a dose-response study.\u003cbr\u003eJ Physiol552(Pt 1):315-24.\u003c\/p\u003e\n\u003cp\u003eTipton, K., Borsheim, E., Wolf, S., Sanford, A. \u0026amp; Wolfe, R. (2003)\u003cbr\u003eAcute response of net muscle protein balance reflects 24-h balance after exercise and amino acid ingestion \u003cbr\u003eAmerican Journal of Physiology, 284(1), E76-E79.\u003c\/p\u003e\n\u003cp\u003eMacLean, D. A., Graham, T. E. \u0026amp; Saltin, B. (1994)\u003cbr\u003eBranched-chain amino acids augment ammonia metabolism while attenuating protein breakdown during exercise.\u003cbr\u003eAm. J. Physiol. 267: E1010...E1022\u003c\/p\u003e\n\u003cp\u003eAdibi, S., Gary, S., Menden, E. (1967)\u003cbr\u003eThe kinetics of amino acid absorption and alteration of plasma composition of free amino acids after intestinal perfusion of amino acid mixtures\u003cbr\u003eAmerican Journal of Clinical Nutrition, 20, 24-33\u003c\/p\u003e\n\u003cp\u003eNosaka, K. (2003)\u003cbr\u003eMuscle soreness and amino acids.\u003cbr\u003eTraining J. 289:24-28.\u003c\/p\u003e\n\u003cp\u003eVolpi E, Sheffield-Moore M, Rasmussen BB, and Wolfe RR. (2001)\u003cbr\u003eBasal muscle amino acid kinetics and protein synthesis in healthy young and older men \u003cbr\u003eJAMA 286: 1206...1212\u003c\/p\u003e\n\u003cp\u003eHan LK, Gong XJ, Kawano S, Saito M, Kimura Y, Okuda H. \u003cbr\u003eAntiobesity actions of Zingiber officinale Roscoe \u003cbr\u003eYakugaku Zasshi. 2005 Feb;125(2):213-7\u003c\/p\u003e\n\u003cp\u003eYoung, H. V., Luo, Y. L., Cheng, H. Y., Hsieh, W. C., Liao, J. C. and Peng, W. H. (2005). \u003cbr\u003eAnalgesic and... activities of [6]-gingerol. \u003cbr\u003eJ Ethnopharmacol 96 (1): 207-210.\u003c\/p\u003e\n\u003cp\u003eDunnett M, Harris RC. \u003cbr\u003eInfluence of oral beta-alanine and L-histidine supplementation on the carnosine content of the gluteus medius \u003cbr\u003eEquine Vet J Suppl. 1999 Jul;30:499-504.\u003c\/p\u003e\n\u003cp\u003eMaynard LM, Boissonneault GA, Chow CK, Bruckner GG. \u003cbr\u003eHigh levels of dietary carnosine are associated with increased concentrations of carnosine and histidine in rat soleus muscle \u003cbr\u003eJ Nutr. 2001 Feb;131(2):287-90\u003c\/p\u003e\n\u003cp\u003eTakashi Nagasawa, Tatsuji Yonekura, Naoyuki Nishizawa and David D. Kitts \u003cbr\u003eIn vitro and in vivo inhibition of muscle lipid and protein oxidation by carnosine \u003cbr\u003eMolecular and Cellular Biochemistry 225: 29-34, 2001\u003c\/p\u003e\n\u003cp\u003eTallon MJ, Harris RC, Boobis LH, Fallowfield JL, Wise JA. \u003cbr\u003eThe carnosine content of vastus lateralis is elevated in resistance-trained bodybuilders. \u003cbr\u003eJ Strength Cond Res. 2005 Nov;19(4):725-729\u003c\/p\u003e\n\u003cp\u003eSuzuki Y, Ito O, Mukai N, Takahashi H, Takamatsu K. \u003cbr\u003eHigh level of skeletal muscle carnosine contributes to the latter half of exercise performance during 30-s maximal cycle ergometer sprinting \u003cbr\u003eJpn J Physiol. 2002 Apr;52(2):199-205\u003c\/p\u003e\n\u003cp\u003eBalon TW and Nadler JL. \u003cbr\u003eNitric oxide is present from incubated skeletal muscle preparations \u003cbr\u003eJ Appl Physiol 77: 2519-2521, 1994\u003c\/p\u003e\n\u003cp\u003eBalon TW and Nadler JL. \u003cbr\u003eEvidence that nitric oxide increases glucose transport in skeletal muscle \u003cbr\u003eJ Appl Physiol 82: 359-363, 1997\u003c\/p\u003e\n\u003cp\u003eWagenmakers, A. (1998). \u003cbr\u003eMuscle amino acid metabolism at rest and during exercise: role in human physiology and metabolism \u003cbr\u003eExercise and Sport Sciences Reviews, 26, 287-314\u003c\/p\u003e\n\u003cp\u003eTipton, K. \u0026amp; Wolfe, R. (1998) \u003cbr\u003eExercise-induced changes in protein metabolism \u003cbr\u003eActa Physiology Scandinavia, 162(3), 377-387\u003c\/p\u003e\n\u003cp\u003eWolfe, R. (2001) \u003cbr\u003eEffects of amino acid intake on anabolic processes \u003cbr\u003eCanadian Journal of Applied Physiology, S26, S220-S227\u003c\/p\u003e\n\u003cp\u003eWolfe, R. (2001) \u003cbr\u003eControl of muscle protein breakdown: effects of activity and nutritional states.\u003cbr\u003eInternational Journal of Sport Nutrition and Exercise Metabolism, S11, S164-S169\u003c\/p\u003e\n\u003cp\u003eBiolo, G., Tipton, K., Klein, S. \u0026amp; Wolfe, R. (1997)\u003c\/p\u003e\n\u003cp\u003eAn abundant supply of amino acids enhances the metabolic effect of exercise on muscle protein \u003cbr\u003eAmerican Journal of Physiology, Endocrinology, and Metabolism, 273, E122-E129\u003c\/p\u003e","brand":"1DISCONTINUED","offers":[{"title":"Juicy Grape \/ 45 Servings","offer_id":17460313358394,"sku":"3770017","price":38.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0133\/8576\/0826\/products\/controlled-labs-purple-wraath-3770017-319341.jpg?v=1701817554"},{"product_id":"ohyeah-promino-plus-30-packets","title":"Promino Plus 30 Packets","description":"\u003cdiv align=\"center\"\u003e\n\u003ch2\u003e\u003cimg class=\"img-responsive\" src=\"\/\/cdn.shopify.com\/s\/files\/1\/0133\/8576\/0826\/files\/image_catBRAND_ISS_RESEARCH_largeImage.jpg\"\u003e\u003c\/h2\u003e\n\u003ch2\u003eISS Research Promino Plus\u003c\/h2\u003e\n\u003c\/div\u003e\nPromino Plus is a two part system: First: AM formula designed to help start the day mentally alert. Second: PM formula designed to gently assist in recovery and relaxation. And now, with a new advanced flavor system. AM Formula: Proprietary AM Blend: Containing Endo-Pro Plus (Taurine and Gaba), Procosanoi, [Trimethybanthine (Caffeine)], L-Glutamine, L-Arginine, L-Tyrosine, L-Lysine, L-Theanine, Succinic Acid. PM Formula: Proprietary PM Blend: Containing Endo-Pro Plus (Taurine and Gaba), L-Glutamine, L-Arginine, L-Tyrosine, L-Lysine, L-Theanine, Succinic Acid.\u003cbr\u003e\u003cbr\u003e\u003cbr\u003e**This is an HGH Supplement not actual HGH.\u003cbr\u003e\u003cbr\u003ePAYPAL NOTICE: Due to PayPal's restrictions, the PayPal payment method can not be used for this HGH-related product. Please choose to pay by credit card or other payment option\u003cbr\u003e\u003cbr\u003e\n\u003cdiv style=\"text-align: center;\"\u003e\n\u003cimg class=\"img-responsive\" src=\"\/\/cdn.shopify.com\/s\/files\/1\/0133\/8576\/0826\/files\/iss_research_3.jpg\"\u003e\u003cbr\u003e\u003cbr\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"text-align: center;\"\u003e\u003c\/div\u003e\n\u003cdiv style=\"text-align: center;\"\u003e\u003c\/div\u003e","brand":"1DISCONTINUED","offers":[{"title":"Fruit Punch","offer_id":17498999619642,"sku":"100133","price":48.09,"currency_code":"USD","in_stock":true},{"title":"Orange","offer_id":17498999652410,"sku":"100097","price":48.09,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0133\/8576\/0826\/products\/100097m-2.jpg?v=1605270560"},{"product_id":"core-nutritionals-abcd-bcaa-energy","title":"Core ABCD BCAA + Energy","description":"\u003cp\u003e\u003cimg alt=\"Core ABCD Banner\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0133\/8576\/0826\/files\/core-abcd-banner_compressed.jpg?v=1599074252\"\u003e\u003c\/p\u003e\n\u003cp\u003eAmino acid products with a caffeine or energy component are very popular these days. There’s only one problem: almost none of them contain a solid serving of amino acids, and most don’t contain BCAAs at all! Don’t get us wrong, we love EAAs – but when you think “amino acid product,” are you really thinking cysteine? Us neither.\u003c\/p\u003e\n\u003cp\u003eSo, in classic Core style, we did something about it: we created Core ABCD, the amino and caffeine product with actual BCAAs, at a full serving size. But we of course didn’t stop there. We included CarnoSyn® beta-alanine, to provide you muscle energy and endurance – along with the caffeine in our Drive™ energy blend. We included N-Acetyl-Tyrosine for all its important roles in metabolism and neurohormone production. We included Acetyl-L-Carnitine, to keep that carbohydrate and fat metabolism rolling. And of course, we included not only caffeine (which all the other guys do), but also choline bitartrate – to enhance focus along the way.\u003c\/p\u003e\n\u003cp\u003eCore ABCD is the premier and most complete product in its category, hands down. No product of its type offers as much for such little cost: it’s an energy product, an endurance product, and a complete amino acid product all in one.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBranched-Chain Amino Acids\u003c\/strong\u003e\u003cbr\u003e\u003cbr\u003eIf one were to think of the body as a construction project, amino acids would be the most basic building materials: raw lumber, mortar, bricks, and so on. While the assembly of these building blocks is of course critically important to the function of the building – and one of the amino acids, leucine, controls its own assembly – the quality and availability of the materials themselves is arguably more important. Not enough concrete? The foundation cracks and the building falls.\u003cbr\u003e\u003cbr\u003eYour body is the exact same way. It is comprised of various amino acids, both essential and non-essential, that comprise the cellular basis of each and every cell in your body. When it comes down to skeletal muscle, the three most important are known as the BCAAs – or branch chained amino acids. Comprised of leucine, isoleucine, and valine, these three little amino acids effectively control the rate at which your muscle grows (hypertrophies), its contractile force, its endurance, and so on – to say they are massively important is an understatement. For this reason, they form the basis of any competently-designed supplement protocol.\u003cbr\u003e\u003cbr\u003eCollectively, as stated above, the branch-chained amino acids leucine, isoleucine, and valine are famous for their role in skeletal muscle protein synthesis and metabolism, and additionally comprise approximately one-third of all skeletal muscle protein. Of the three, leucine is both the most physiologically important with respect to muscle mass, and the most extensively studied. Data on leucine demonstrate this amino acid plays critical roles in stimulating skeletal muscle protein synthesis, and ribosomal biogenesis and assembly (the literal building of muscle tissue), along with playing a lesser role in insulin signaling and gluconeogenic processes. As a result of these diverse roles, leucine has been demonstrated to significantly stimulate skeletal muscle protein synthesis, and attenuate protein degradation, by both insulin-mediated and non-insulin mediated mechanisms.\u003cbr\u003e\u003cbr\u003eLeucine’s insulin-mediated effects are largely the result of its activation of the classical insulin receptor substrate (IRS)\/phosphatidylinositol (PI) 3-kinase (PI3K)\/Akt\/mTOR signal transduction pathway. In this pathway, the bonding of a substrate (glucose) eventually activates a compound known as Akt. Once phosphorylated and activated, Akt signals the release of the famous mammalian target of rapmycin (mTOR). mTOR then increases the translation of muscle-cell ribosomal proteins that increase ribosome biogenesis, which is the literal production of proteins. Leucine has additionally been shown to positively regulate protein synthesis independent of insulin. In certain trials where rapamycin and leucine were co-administered, rapamycin showed only partial inhibition of leucine’s effects on muscle protein synthesis.\u003cbr\u003e\u003cbr\u003eIn more practical terms, there is a significant body of evidence demonstrating the positive effect of BCAA’s on athletic performance. Extensive studies in exercise-trained populations reveal that, collectively, BCAA’s may:\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eReduce total muscle soreness after intense resistance training, and\/or further delay its onset.\u003c\/li\u003e\n\u003cli\u003eDecrease muscle recovery time between bouts of intense resistance exercise training.\u003c\/li\u003e\n\u003cli\u003eIncrease lean body mass when used daily, in conjunction with diet and exercise.\u003c\/li\u003e\n\u003cli\u003eWhile products with larger BCAA ratios (ratio of leucine, to isoleucine, to valine) have recently flooded the market, Core Nutritionals has remained with the gold standard of 2:1:1. This decision is made in recognition of the fact that, for all its potential benefits, there is no evidence demonstrating a realized effect of a larger BCAA ratio – and in fact, all the benefits mentioned above derive from evidence using the gold standard 2:1:1 ratio.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eCarnoSyn® Beta-Alanine\u003c\/strong\u003e\u003cbr\u003e\u003cbr\u003eCarnosine is a bit of an odd duck: we know that it is crucial for muscle function and that dietary sources of carnosine are essential, but we don’t know precisely how it's working. Moreover, for decades, we had no idea how to increase intramuscular concentrations, as exogenous carnosine sources degraded in the body so fast as to be effectively useless. \u003cbr\u003e\u003cbr\u003eEnter beta-alanine. Simply a different iteration of one of the amino acids that comprises carnosine itself (alanine), beta-alanine has proven to be the most effective means of significantly increasing intramuscular concentrations of carnosine – and therefore of promoting all of carnosine’s various beneficial effects on muscle performance. If that weren’t enough, beta-alanine has also demonstrated beneficial physiological effects independent of its parent compound. In order to understand why, though, we need to first understand some of the basics behind carnosine itself. \u003cbr\u003e\u003cbr\u003eCarnosine, a cytoplasmic dipeptide synthesized from the precursors L-histidine and l-alanine, is present in high concentrations in skeletal muscle and plays a pivotal role as a “chemical buffer” in myocytes (muscle cells). It has long been known that carnosine concentrations are highest in glycolytic, rather than oxidative muscle fibers (roughly speaking, explosive vs., endurance muscle fibers, respectively), and thus long hypothesized that this amino acid is required for sustained performance during supramaximal exercise. Recent research demonstrates that carnosine exerts its physiological effects in long hypoxic (low oxygen) drives by functioning as a high-capacity pH buffer in skeletal muscle, preventing the pH ratio of plasma from dropping too low – and therefore preventing crucial pH-dependent processes such as protein synthesis from being inhibited by acidosis. \u003cbr\u003e\u003cbr\u003eDespite its critical role in skeletal muscle anaerobic performance, intramyocellular synthesis of carnosine is rate-limited by the availability of l-alanine. Unfortunately, the majority of literature demonstrates that attempting to increase intramuscular levels of carnosine via either direct carnosine or alanine supplementation is largely ineffective due to carnosine\/alanine pharmacokinetics. Enter beta-alanine. Research with beta-alanine demonstrates consistent and dose-dependent increases to intramuscular carnosine concentrations with beta-alanine supplementation, with certain studies showing an increase of 40-60% with chronic administration. These same literature reveal a synergistic effect of exercise on beta-alanine supplementation, whereby the muscle adaptive changes associated with resistance training promote further intramuscular carnosine production in response to beta-alanine supplementation.\u003cbr\u003e\u003cbr\u003eIn simpler language, this essentially means that beta-alanine is a dietary supplement that promotes its own effects in combination with exercise. As you exercise, you simultaneously intensify beta-alanine’s physiological actions – both directly, as well as in the production of intramuscular carnosine. Once ingested, beta-alanine’s exercise-specific beneficial activity is well-established. Elevation of intramuscular carnosine content via beta-alanine supplementation has been show to improve performance in the following ways:\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eBoth acute and chronic increases in total work capacity, measured by total volume during exercise sessions.\u003c\/li\u003e\n\u003cli\u003eHighly significant increases to TTE (total time to exhaustion), one of the most accurate and comprehensive measures of endurance. In various trials, beta-alanine supplementation has been shown to increase TTE by upwards of 20%.\u003c\/li\u003e\n\u003cli\u003eIncreases to total muscle power output in both acute and chronic trials, suggesting that beta-alanine’s most significant benefit is to those engaging in power-dependent resistance training.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eIn total, a significant body of research exists to suggest that beta-alanine may significantly increase muscle power output, strength, training volume and output, overall performance in hypoxic (oxygen-deprived) conditions, and peak VO2 max (oxygen holding capacity).\u003cbr\u003e\u003cbr\u003eThese myriad benefits make beta-alanine both one of the most-studied, and most well-rounded dietary supplements. Beta-alanine not only has direct, actionable physiological effects, but also promotes critical muscle physiologic adaptations that promote its own effects.\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eAcetyl-L-Carnitine\u003c\/strong\u003e\u003cbr\u003e\u003cbr\u003eAcetyl-L-carnitine has been shown to:\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePromote fatty acid and carbohydrate metabolism\u003c\/li\u003e\n\u003cli\u003eBe involved in brain processes such as mood and memory\u003c\/li\u003e\n\u003cli\u003ePlay a key role in protein synthesis\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eAcetyl-L-Carnitine (ALCAR) is a little bit like your 401K: you need it, you know you should pay attention to it, but it’s not exactly the sexiest topic. We know; we feel you! But we also know that ALCAR is one of the most fascinating, useful, and physiologically exciting workout supplements on the planet. You’re hard-pressed to find a single other ingredient that is involved in so many critical bodily processes: fatty acid and carbohydrate metabolism, neurotransmission, exercise performance and capacity, brain function – the list goes on! So, like your 401K contribution, don’t forget to pay into your ALCAR fund. \u003cbr\u003e\u003cbr\u003eL-carnitine is a derivative of the amino acid lysine and, as certain conditions outpace the body’s ability to produce it, l-carnitine is considered a conditionally essential amino acid. While endogenous biosynthesis of l-carnitine from the amino acids lysine and methionine is sufficient for essential processes – along with dietary sources of carnitine from protein-rich red meat, for example – dietary supplementation of carnitine may pose benefits in certain physiological conditions. \u003cbr\u003e\u003cbr\u003eUnfortunately, due to excess metabolism of l-carnitine by microorganisms in the small intestine, exogenous supplementation with oral l-carnitine has proved ineffective. ALCAR, an acetylated version of l-carnitine, has considerably higher oral bioavailability, due likely to only partial hydrolytic metabolism. Once in the bloodstream, ALCAR plays a fundamental role in the production of energy, acting as the catalyst for the beta-oxidation of long-chain fatty acids by the mitochondria; regulating the CoA to Acyl-CoA ratio (necessary for the production of ATP); and the metabolism of carbohydrates. ALCAR also is an excitatory agent for neurons, increases neuronal transmission, and increases the production of neurotransmitters and neurohormones such as dopamine and serotonin.\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eN-Acetyl-Tyrosine\u003c\/strong\u003e\u003cbr\u003e\u003cbr\u003eTyrosine is amongst a class of amino acids known as ‘non-essential’ amino acids, so-called because the body can produce them endogenously, and it is therefore not essential to consume dietary tyrosine. That said, tyrosine is also what is known as a conditionally essential amino acid; conditionally-essential because, along with glucose and ammonia, the synthesis of tyrosine additionally requires adequate levels of phenylalanine. Once synthesized, tyrosine is one of the most critical amino acids, given its prominent role as a substrate in the synthesis of the catecholamines dopamine, norepinephrine, and epinephrine, in addition to both T3 (triiodothyronine) and T4 (thyroxine) thyroid hormones.\u003cbr\u003e\u003cbr\u003eIn studies on stress modulation, tyrosine has been demonstrated to reverse stress-induced norepinephrine depletion and the depressant-behavioral effects normally associated with it. In simpler terms, tyrosine may, in certain conditions, dampen the extent to which norepinephrine is removed from the bloodstream during a stress event. In simpler terms still, tyrosine may help to mitigate the sense of depletion and fatigue felt at the end of a workout.\u003cbr\u003e\u003cbr\u003eTyrosine may also play important metabolic functions, mostly related to its role in synthesizing compounds that stimulate the nervous system. While not traditionally considered a sympathomimetic amine, studies which have coadministered tyrosine and stimulants demonstrate a synergistic effect. These studies suggest that tyrosine may potentiate the effects of both endogenous and supplemental norepinephrine and its mimetics (in the case of exogenous use) with respect to lipolysis, thermogenesis, and energy expenditure. Meaning that tyrosine may play a role in assisting norepinephrine to break up triglycerides and increase body heat transiently.\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eCholine Bitartrate\u003c\/strong\u003e\u003cbr\u003e\u003cbr\u003eCholine is an essential nutrient involved in numerous metabolic pathways, including DNA regulation and repair, protein function, and metabolism. Perhaps most importantly, the critical neurotransmitter acetylcholine is produced directly from free choline via cholinergic neurons. Acetylcholine is then responsible for a number of functions itself, most crucially as the compound which induces muscular contraction, and as the neuromodulator is partially responsible for modulating risk\/reward, arousal, and enhancing memory.\u003cbr\u003e\u003cbr\u003eCholine’s essential role as a substrate for acetylcholine, and therefore brain development, is well documented in animal models. These studies demonstrate that levels of free maternal choline have a direct and fundamental impact on prenatal brain development, with the enhancements or deficits lasting into adulthood. Choline’s enhancing effect is particularly prominent in the hippocampus. In humans, the hippocampus is primarily involved in the consolidation of memory (taking short, episodic memory and translating it into long-term memory) and the learning of new information. Acetylcholine is a critical component in these processes, as mentioned above, and choline may therefore play a potential role in these processes as well by providing the substrate for acetylcholine synthesis.\u003cbr\u003e\u003cbr\u003eTartaric acid occurs naturally in the food source, while its salt derivatives (tartrate, for example) have been used as acidulants, antioxidant synergists, buffers, and sequestrants. As free base choline is rapidly destroyed in metabolism, attaching a salt to enhance absorption is necessary. The bitartrate salt addition preserves choline from being destroyed during metabolism. \u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eCaffeine Anhydrous\u003c\/strong\u003e\u003cbr\u003e\u003cbr\u003eCaffeine is one of the most widely consumed, and perhaps some of the most reviewed, psychoactive compounds. Their physiological effects in a range of areas have been well-documented, including exercise performance, information processing, alertness and mood enhancement, attention, and awareness, along with its anti-lipogenic and lipolytic abilities.\u003cbr\u003e\u003cbr\u003eMost importantly to Core ABCD, caffeine has been shown to have significant effects on exercise performance, even with ingestion in servings as small 3 to 9mg\/kg\/bw\/day (the equivalent of 2 cups of standard coffee, for a 170lb male). In endurance training, possible explanations for caffeine’s performance-enhancing effects lie in its metabolic effects on both lean and fat tissue. It is suggested that caffeine’s potent lipolytic (the breakdown of fat tissue into fatty acids) and oxidative (the actual ‘burning’ of fat) action allow the body to utilize these sources during prolonged submaximal exercise. As a consequence, muscle glycogen is spared and available for use later in the training session. Practically speaking, this means caffeine is forcing your body to preferentially use fat tissue as a fuel source while sparing the glycogen which gives you the full-bodied look!\u003cbr\u003e\u003cbr\u003eIn short-term exercise, caffeine’s demonstrated role in the inhibition of cyclic AMP- phosphodiesterases (PDE), adenosine receptor antagonism, and adrenoreceptor agonism come into play. These three pathways collectively stimulate lipolytic activity, boost fat metabolism, increase metabolic rate and energy expenditure, and regulate the body’s thermogenic activity. The practical results of activating these pathways are increases to the contractile force of both cardiac and skeletal muscle (harder flexion), an increase in energy expenditure (freeing up more caloric energy to be used in contraction), dilation of the vasculature (better blood flow), and improvements to both nitrogen retention and skeletal muscle protein synthesis (key components to muscle building).\u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"Sweet Tea","offer_id":22786845147194,"sku":"1003345","price":29.99,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0133\/8576\/0826\/products\/core-nutritionals-core-abcd-bcaa-energy-1003142-842267.jpg?v=1701816859"},{"product_id":"now-foods-l-lysine","title":"NOW Foods L-Lysine","description":"\u003ch2 data-start=\"492\" data-end=\"539\"\u003e\u003cstrong data-start=\"492\" data-end=\"539\"\u003eEssential Amino Acid for Everyday Nutrition\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp data-start=\"541\" data-end=\"784\"\u003eNOW Foods L-Lysine 500 mg delivers this essential amino acid in a convenient capsule form. Because lysine is not produced by the body, it must be obtained through diet or supplementation making it a popular addition to daily wellness routines.\u003c\/p\u003e\n\u003cp data-start=\"786\" data-end=\"947\"\u003eThis straightforward formula offers a simple way to help maintain consistent intake, especially for those with active lifestyles or specific dietary preferences.\u003c\/p\u003e\n\u003ch3 data-section-id=\"1u4pjq7\" data-start=\"949\" data-end=\"994\"\u003e\u003cstrong data-start=\"953\" data-end=\"994\"\u003eWhy Choose NOW Foods L-Lysine 500 mg?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cul data-start=\"995\" data-end=\"1198\"\u003e\n\u003cli data-section-id=\"ybtarm\" data-start=\"995\" data-end=\"1040\"\u003e\n\u003cp data-start=\"997\" data-end=\"1040\"\u003e\u003cstrong data-start=\"997\" data-end=\"1019\"\u003e500 mg per capsule\u003c\/strong\u003e for easy daily use\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-section-id=\"1b83278\" data-start=\"1041\" data-end=\"1094\"\u003e\n\u003cp data-start=\"1043\" data-end=\"1094\"\u003e\u003cstrong data-start=\"1043\" data-end=\"1067\"\u003eEssential amino acid\u003c\/strong\u003e not produced by the body\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-section-id=\"bzs41b\" data-start=\"1095\" data-end=\"1121\"\u003e\n\u003cp data-start=\"1097\" data-end=\"1121\"\u003e\u003cstrong data-start=\"1097\" data-end=\"1119\"\u003eFree form L-lysine\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-section-id=\"1ce5qd\" data-start=\"1122\" data-end=\"1165\"\u003e\n\u003cp data-start=\"1124\" data-end=\"1165\"\u003e\u003cstrong data-start=\"1124\" data-end=\"1162\"\u003eSupports overall wellness routines\u003c\/strong\u003e*\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-section-id=\"720o0u\" data-start=\"1166\" data-end=\"1198\"\u003e\n\u003cp data-start=\"1168\" data-end=\"1198\"\u003e\u003cstrong data-start=\"1168\" data-end=\"1198\"\u003eNon-GMO and quality tested\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 data-section-id=\"1hv3pcc\" data-start=\"1200\" data-end=\"1232\"\u003e\u003cstrong data-start=\"1204\" data-end=\"1232\"\u003eHow It Fits Your Routine\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp data-start=\"1233\" data-end=\"1419\"\u003eL-Lysine is commonly included in supplement routines focused on balanced nutrition and consistency. It can be taken on its own or alongside other amino acids as part of your daily stack.\u003c\/p\u003e\n\u003cp data-start=\"1421\" data-end=\"1563\"\u003eWhether you're keeping your routine simple or building a well-rounded supplement plan, NOW Foods L-Lysine offers a reliable, no-frills option.\u003c\/p\u003e\n\u003chr data-start=\"1565\" data-end=\"1568\"\u003e\n\u003ch2 data-section-id=\"4uqgsf\" data-start=\"2384\" data-end=\"2415\"\u003e\u003cstrong data-start=\"2387\" data-end=\"2413\"\u003eFAQ\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp data-start=\"2417\" data-end=\"2537\"\u003e\u003cstrong data-start=\"2417\" data-end=\"2441\"\u003eQ: What is L-Lysine?\u003c\/strong\u003e\u003cbr data-start=\"2441\" data-end=\"2444\"\u003eA: L-Lysine is an essential amino acid that must be obtained through diet or supplementation.\u003c\/p\u003e\n\u003cp data-start=\"2539\" data-end=\"2640\"\u003e\u003cstrong data-start=\"2539\" data-end=\"2574\"\u003eQ: When should I take L-Lysine?\u003c\/strong\u003e\u003cbr data-start=\"2574\" data-end=\"2577\"\u003eA: It can be taken daily, depending on your supplement routine.\u003c\/p\u003e\n\u003cp data-start=\"2642\" data-end=\"2779\"\u003e\u003cstrong data-start=\"2642\" data-end=\"2692\"\u003eQ: Can I take L-Lysine with other supplements?\u003c\/strong\u003e\u003cbr data-start=\"2692\" data-end=\"2695\"\u003eA: Yes, it is often used alongside other amino acids and daily wellness supplements.\u003c\/p\u003e\n\u003cp data-start=\"2781\" data-end=\"2909\"\u003e\u003cstrong data-start=\"2781\" data-end=\"2824\"\u003eQ: Is this product vegetarian friendly?\u003c\/strong\u003e\u003cbr data-start=\"2824\" data-end=\"2827\"\u003eA: This depends on the capsule type please refer to the product label for details.\u003c\/p\u003e","brand":"NOW Foods","offers":[{"title":"100 count","offer_id":40227264954426,"sku":"0110","price":7.34,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0133\/8576\/0826\/files\/now-foods-l-lysine-1001228-367958.png?v=1741898146"},{"product_id":"now-foods-l-lysine-1-000-mg","title":"NOW Foods L-Lysine 1,000 mg","description":"\u003cp data-start=\"382\" data-end=\"645\"\u003eNOW Foods L-Lysine 1,000 mg Tablets provide a convenient way to incorporate this essential amino acid into your daily supplement routine. L-Lysine is an amino acid that must be obtained through diet or supplementation and is naturally found in protein-rich foods.\u003c\/p\u003e\n\u003cp data-start=\"647\" data-end=\"930\"\u003eEach tablet delivers \u003cstrong data-start=\"668\" data-end=\"692\"\u003e1,000 mg of L-lysine\u003c\/strong\u003e, offering a simple option for individuals looking to include this amino acid as part of their daily nutrition plan. Amino acids are commonly included in supplement programs designed to complement balanced nutrition and active lifestyles.\u003c\/p\u003e\n\u003cp data-start=\"932\" data-end=\"1089\"\u003eThe tablet format provides consistent servings without the need for powders or additional preparation, making it easy to add to everyday supplement routines.\u003c\/p\u003e\n\u003cp data-start=\"1091\" data-end=\"1267\"\u003eNOW Foods L-Lysine Tablets are produced with carefully selected ingredients and manufactured under strict quality standards to help ensure purity, consistency, and reliability.\u003c\/p\u003e","brand":"NOW Foods","offers":[{"title":"100 Tablets","offer_id":41285284134970,"sku":"0113","price":10.95,"currency_code":"USD","in_stock":false},{"title":"250 Tablets","offer_id":41285284167738,"sku":"0123","price":21.95,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0133\/8576\/0826\/files\/NOWFoods_L-Lysine_1_000mg_100Tablets.png?v=1773260075"}],"url":"https:\/\/tigerfitness.com\/collections\/l-lysine.oembed","provider":"Tiger Fitness","version":"1.0","type":"link"}