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Methylene blue is a powerful compound that has been used for various medical applications for over a century. In recent years, it has gained popularity as a supplement for cognitive enhancement, mitochondrial health, physical performance, and even anti-aging benefits. When combined with other powerful compounds like HPN NAD3 and NAD+ injections, the effects can be further amplified, leading to optimal mental and physical health.
In this article, we’ll explore the science-backed benefits of methylene blue, how it works in the body, and how to use it effectively. We’ll also discuss the ideal dosing strategies for methylene blue, HPN NAD3, and NAD+ injections, including how to adjust dosing based on bodyweight for methylene blue.
Methylene blue is a synthetic dye that has been historically used to treat conditions like methemoglobinemia, a blood disorder. Recently, it has gained attention as a powerful mitochondrial enhancer, improving cellular energy production, cognitive function, and overall performance.
Methylene blue works by improving the efficiency of mitochondrial function. Mitochondria are the energy powerhouses of our cells, and optimizing their function can lead to better brain health, increased physical endurance, and enhanced recovery.
Memory improvement: Methylene blue has been shown to improve both short-term and long-term memory by increasing oxygen availability to brain cells and promoting better neuronal communication.
Increased focus and mental clarity: By improving mitochondrial function in the brain, methylene blue helps increase cognitive function, making it easier to focus and think clearly, especially under stress or fatigue.
Neuroprotection: Methylene blue protects against oxidative stress in brain cells, which is crucial in preventing cognitive decline and neurodegenerative diseases, such as Alzheimer’s and Parkinson’s.
Enhanced endurance and energy production: Methylene blue boosts mitochondrial efficiency, leading to better energy production at the cellular level. This results in improved endurance and reduced fatigue during exercise or physical activity.
Muscle recovery: Methylene blue aids in muscle recovery by supporting mitochondria in muscle cells, speeding up the repair process and reducing recovery time between workouts.
Improved oxygen utilization: Methylene blue increases the oxygen-carrying capacity of blood, which optimizes oxygen utilization at the cellular level, enhancing performance in endurance exercises like running or cycling.
Methylene blue is one of the most powerful supplements for supporting mitochondrial health. As we age, mitochondrial function declines, leading to reduced energy levels, fatigue, and slower recovery. By enhancing mitochondrial efficiency, methylene blue helps counteract these effects, supporting anti-aging benefits at the cellular level.
Studies suggest that methylene blue may help preserve mitochondrial function, enhance tissue repair, and even promote cellular longevity. It could be a key component in slowing down the aging process and maintaining cognitive and physical vitality.
While methylene blue is potent on its own, combining it with HPN NAD3 and NAD+ injections can provide even more significant cognitive and physical benefits. These compounds work together to enhance mitochondrial function, improve energy production, and support optimal health.
HPN NAD3 is a supplement that supports NAD+ (Nicotinamide adenine dinucleotide) levels in the body. NAD+ is essential for energy production, cellular repair, and overall health. Supplementing with HPN NAD3 helps replenish NAD+ reserves, improving mitochondrial efficiency and cellular health. This leads to increased energy, better mental clarity, and improved recovery.
NAD+ injections are a more direct way to raise NAD+ levels. These injections provide immediate support for mitochondrial function, helping with energy production and cognitive performance. When combined with methylene blue, which enhances mitochondrial function, NAD+ injections help optimize both brain and body health.
I (Marc Lobliner) personally use this combination—methylene blue, HPN NAD3, and NAD+ injections—to maintain peak performance and recovery, both mentally and physically.
Here are the general dosing recommendations for all three compounds, including bodyweight-specific dosing for methylene blue:
Methylene blue is typically taken in small doses for cognitive enhancement and physical performance. The recommended dosage can vary based on body weight and individual tolerance.
Standard dose: A typical dose is 0.5 to 1 mg per kg of body weight. For example:
For someone weighing 70 kg (154 lbs): The typical dose would be 35-70 mg.
For someone weighing 90 kg (198 lbs): The typical dose would be 45-90 mg.
This dose can be taken once per day or divided into smaller doses throughout the day.
Note: It is essential to start with a lower dose and gradually increase it to assess individual tolerance. For high doses or extended use, it is crucial to consult with a healthcare provider.
For HPN NAD3, the typical dose is 1-2 capsules per day, depending on individual needs. Some individuals may start with one capsule daily and gradually increase to two capsules based on their energy and recovery needs.
NAD+ injections are typically administered by a healthcare provider. The dose usually ranges from 250 mg to 500 mg per injection, depending on the individual’s health goals. NAD+ injections can be taken once a week or bi-weekly. Higher doses may be used for individuals undergoing detox programs or intensive biohacking protocols, but this should be done under medical supervision.
Methylene blue is a powerful supplement that supports cognitive function, physical performance, and mitochondrial health. By enhancing energy production at the cellular level, it improves brain function, increases endurance, and aids in muscle recovery. When stacked with HPN NAD3 and NAD+ injections, its effects are amplified, leading to optimal health and performance.
I personally use this stack to maintain peak mental clarity, recovery, and overall vitality, and I highly recommend it for anyone looking to optimize their cognitive and physical performance.
For more information and to purchase HPN NAD3, visit HPN NAD3 at Tiger Fitness.