Yohimbine works by widening blood vessels to increase blood flow in the body. It is also thought to increase fatty acid mobilization. Yohimbe stimulates the central nervous system by causing the body to produce more noradrenaline. Its popularity has been ignited not only by it's claimed effects to elevate libido, but also new research that shows it could be an herb with very effective antioxidant potential.

Nitric Oxide levels also increase which can dilate blood vessels and can potentially allow for increased blood flow. The combination of both increased blood flow and energy contribute to yohimbine HCL's effectiveness to help maintain a healthy heart, but yohimbe also has been shown to decrease fat synthesis in the body by increasing fatty acid mobilization.