In a recent study released in the Journal of Applied Physiology, the oral prohormone 1-androstene-3b-ol-17-one which converts in the liver to 1-Testosterone was as potent milligram-for-milligram to Testosterone Enanthate, the gold standard for Testosterone products. Very few dietary supplements have been subjected to a clinical study. However, the active prohormone 1-androstene-3b-ol-17-one was the subject of a clinical study at the West Texas A&M University, the California Baptist University and the University of Texas at Austin. 

The results showed 1-androstene-3b-ol-17-one to be significantly more powerful than it would appear structurally. The 9 males gained an average lean mass of 10.4 lbs and an increase in strength of 92.2 lbs in total load on bench/squat/deadlift. These are significant gains from a prohormone. The researchers concluded that the prohormone supplement contributed to robust improvements in muscle mass and strength in resistance trained. Although repeated studies are necessary to substantiate the efficacy of any compound, it’s safe to say that 1-androstene-3b-ol-17-one definitely packs a punch.